THE STATE OF THE CARDIOVASCULAR SYSTEM IN CHILDREN WITH GASTROENTEROLOGICAL PATHOLOGICAL DISORDERS

Abstract

Abstract

M.A Gonchar, E.V. Omelchenko, A.S. Senatorova, M.I. Strelkova, A.E. Silicheva, M.N. Ermolaev

THE STATE OF THE CARDIOVASCULAR SYSTEM IN CHILDREN WITH GASTROENTEROLOGICAL PATHOLOGICAL DISORDERS

Kharkiv National Medical University, Ukraine

 

The article deals with the main approaches to the stratification of cardiovascular risk condition of children with gastroenterological disorders; the unmodified risk factors identified by the "Genetic Questionnaire" have been discussed; the role of polymorphism of the folate cycle genes in the development of children’s cardiovascular disease has been identified.

 

Key words: cardiovascular risk, pediatric, cardiovascular system, gastroenterological diseases.

 

Резюме

Гончарь М.О., Омельченко О.В., Сенаторова Г.С., Стрелкова М.І., СілічеваА.Е., Єрмолаєв М.М.

СТАН СЕРЦЕВО-СУДИННОЇ СИСТЕМИ У ДІТЕЙ З ГАСТРОЕНТЕРОЛОГІЧНОЮ ПАТОЛОГІЄЮ

Харківський національний медичний університет

 

В статті викладено основні підходи до стратифікації кардиоваскулярного ризику у дітей с гастоентерологічною патологією. Зроблено акцент на немодифікованих факторах ризику, виявлених за допомогою «Генетичного опитувальника». Визначена роль поліморфізму генів фолатного циклу у розвитку серцево-судинних захворювань у дітей.

 

Ключові слова:кардіоваскулярний ризик, діти, серцево-судинна система,гастоентерологічна патологія.

 

Резюме

Гончарь М.О., Омельченко О.В., Сенаторова Г.С., Стрелкова М.І., СілічеваА.Е., Єрмолаєв М.М.

СОСТОЯНИЕ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ У ДЕТЕЙ С ГАСТРОЭНТЕРОЛОГИЧЕСКОЙ ПАТОЛОГИЕЙ

Харьковский национальный медицинский университет

 

В статье изложены основные подходы к стратификации кардиоваскулярного риска у детей с гастоэнтерологической патологией. Сделан акцент на немодифицированных факторах риска, выявленных с помощью «генетической опросника». Определена роль полиморфизма генов фолатного цикла в развитии сердечно-сосудистых заболеваний у детей.

 

Ключевые слова: кардиоваскулярный риск, дети, сердечно-сосудистая система, гастоэнтерологическая патология.

https://doi.org/10.35339/ic.3.1.30-34
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References

Conroy, R. M., Pyörälä K., Fitzgerald, A.P. et al.

Estimation of ten-year risk of fatal cardiovascular disease

in Europe: the SCORE project // Eur. Heart J. – 2009. - №

(11). – 987-1003.

Kathiresan S. Genetics of human cardiovascular

disease // Cell. – 2012. – Mar 16. – № 148(6). – Р. 1242–57.

Mancia, G. Total cardiovascular risk: a new treatment

concept //J. Hypertens. Suppl. – 2015. – № 24 (2). –

P. 17–24.

Willerson, J. T., Ridker P.M. Inflammation as a

cardiovascular riskfactor // Circulation. – 2014. – № 109

(21, Suppl. 1). – 112–110.

Verdecchia, P., Angeli F., Pittavini L. et al. Regression

of leftventricular hypertrophy and cardiovascular

risk changes in hypertensive patients // Ital. Heart J. –

– № 5 (7). – 505–510.

Association between decreased vitamin levels and

MTHFR, MTR and MTRR gene polymorphisms as determinants

for elevated total homocysteine concentrations in

pregnant women / P. R. Barbosa, S. P. Stabler, A. L. Machado

[et al.] // Eur. J. Clin. Nutr. − 2011. – Vol. 62, № 8.

– 1010−1021.

Genetic polymorphisms involved in folate metabolism

and concentrations of methylmalonic acid and folate

on plasma homocysteine and risk of coronary artery disease

/ M. Biselli, A. R. Guerzoni, M. F. de Godoy [et al.]

// J. Thromb. Thrombolysis. – 2010. – Vol. 29, № 1. –

−40.

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