MANDIBULAR OSTEOMETRIC INDEXES IN PATIENTS WITH PERIODONTITIS DEPENDING ON THE LEVEL OF VITAMIN D
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How to Cite

Novoshytskyy, V. E., & Mazur, I. (2017). MANDIBULAR OSTEOMETRIC INDEXES IN PATIENTS WITH PERIODONTITIS DEPENDING ON THE LEVEL OF VITAMIN D. Inter Collegas, 4(1), 42-44. https://doi.org/10.35339/ic.4.1.42-44

Abstract

MANDIBULAR OSTEOMETRIC INDEXES IN PATIENTS WITH PERIODONTITIS DEPENDING ON THE LEVEL OF VITAMIN D

Novoshytskyy V. E., Mazur I. P. 

Recent studies have reported a relationship between vitamin D level, bone tissue and periodontitis. The aim of study was to determine mandibular osteometric indices in patients with periodontitis depending on the level of vitamin D. We have examined 95 patients with periodontitis. Patients were divided into 3 groups according to 25-hydroxyvitamin-D concentration in plasma. All patients were examined to determine vitamin D level and mandibular osteometric indices. Mandibular height in the canine area in patients with vitamin D sufficiency was the lowest and was 27.33(25.15-29.02)mm. Mandibular height in patients with vitamin D deficiency and insufficiency was 28.04(25.91-29.78)mm and 29.03(26.70-31.21)mm, respectively. Mandibular body height in the canine area in patients with GP and vitamin D deficiency, insufficiency and sufficiency was 16.68(14.95-18.45)mm, 17.34(15.74-19.42)mm and 15.93(14.65-17.23)mm, respectively and alveolar bone height in canine area was 11.55(9.53-12.85)mm, 11.21(10.00-13.81)mm and 11.21(9.69-12.75)mm, respectively. Thus, the increase of mandibular height in patients with periodontitis who had vitamin D deficiency and insufficiency occurred by the increase of mandibular body height.

KeyWords:  periodontitis, vitamin D, bone tissue, mandible, osteometric indices.

 

ОСТЕОМЕТРИЧНІ ПОКАЗНИКИ НИЖНЬОЇ ЩЕЛЕПИ У ПАЦІЄНТІВ ІЗ ГЕНЕРАЛІЗОВАНИМ ПАРОДОНТИТОМ В ЗАЛЕЖНОСТІ ВІД РІВНЯ ВІТАМІНУ D

Новошицький В. Є., Мазур І. П.

Останнім часом повідомляється про взаємозв’язок між рівнем вітаміну D, кістковою тканиною та генералізованим пародонтитом (ГП). Метою дослідження було визначити остеометричні показники нижньої щелепи (НЩ) у пацієнтів із ГП в залежності від рівня вітаміну D. В дослідження були включені 95 пацієнтів із ГП віком від 25 до 68 років. Пацієнти були розподілені на 3 групи в залежності від рівня вітаміну D. Всім пацієнтам було проведено визначення рівня вітаміну D та остеометричних показників НЩ. Висота НЩ в ділянці ікол була найнижча у пацієнтів із ГП, які мають достатній рівень вітаміну D та становила 27,33(25,15-29,02)мм. А висота НЩ при дефіциті та недостатності становила 28,04(25,91-29,78)мм та 29,03(26,70-31,21)мм відповідно. Висота тіла НЩ в ділянці ікол у пацієнтів із ГП при дефіциті, недостатності та достатності вітаміну D становила 16,68(14,95-18,45)мм, 17,34(15,74-19,42)мм та 15,93(14,65-17,23)мм відповідно, а висота альвеолярного відростка НЩ в ділянці ікол становила 11,55(9,53-12,85)мм, 11,21(10,00-13,81)мм та 11,21(9,69-12,75)мм відповідно. Отже, збільшення висоти НЩ у пацієнтів із ГП при дефіциті та недостатності вітаміну D відбувається за рахунок збільшення висоти тіла НЩ.

Ключові слова: генералізований пародонтит, вітамін D, кісткова тканина, нижня щелепа, остеометричні індекси

  

ОСТЕОМЕТРИЧЕСКИЕ ПОКАЗАТЕЛИ НИЖНЕЙ ЧЕЛЮСТИ У ПАЦИЕНТОВ С ГЕНЕРАЛИЗОВАННЫМ ПАРОДОНТИТОМ В ЗАВИСИМОСТИ ОТ УРОВНЯ ВИТАМИНА D

Новошицкий В. Е.,  Мазур И. П.

В последнее время сообщается о взаимосвязи между уровнем витамина D, костной тканью и генерализованным пародонтитом (ГП). Целью исследования было определение остеометрических показателей нижней челюсти (НЧ) у пациентов с ГП в зависимости от уровня витамина D. В исследование были включены 95 пациентов с ГП в возрасте от 25 до 68 лет. Пациенты были разделены на 3 группы в зависимости от уровня витамина D. Всем пациентам было проведено определение уровня витамина D и остеометрических показателей НЧ. Высота НЧ в области клыков была самая низкая у пациентов с ГП, которые имеют достаточный уровень витамина D и составила 27,33(25,15-29,02)мм. Высота НЧ при дефиците и недостаточности составляла 28,04(25,91-29,78)мм и 29,03(26,70-31,21)мм, соответственно. Высота тела НЧ в области клыков у пациентов с ГП при дефиците, недостаточности и достаточности витамина D составляла 16,68(14,95-18,45)мм, 17,34(15,74-19,42)мм и 15,93(14,65-17,23)мм, соответственно. Высота альвеолярного отростка НЧ в области клыков составляла 11,55(9,53-12,85) мм, 11,21(10,00-13,81)мм и 11,21(9,69-12,75) мм соответственно. Таким образом, увеличение высоты НЧ у пациентов с ГП при дефиците и недостаточности витамина D происходит за счет увеличения высоты тела НЧ.

Ключевые слова: генерализованный пародонтит, витамин D, костная ткань, нижняя челюсть, остеометрические индексы

https://doi.org/10.35339/ic.4.1.42-44
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References

Stein, S.H., Tipton, D.A. (2011) Vitamin D and its impact on oral health - an update J Tenn Dent Assoc, 91(2), 30-3;

Ponsonby, A., Lucas, R., van der Mei, I (2005) UVR, vitamin D and three autoimmune diseases—multiple sclerosis, type 1 diabetes, rheumatoid arthritis. Photochem. Photobiol, 81, 1267–1275.

Harris, S.S. (2005) Vitamin D in type 1 diabetes prevention J. Nutr., 135, 323–325.

Pittas, A.G., Lau, J., Hu, F.B., Dawson-Hughes, B. (2007) The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J. Clin. Endocrinol. Metab., 92, 2017–2029.

Povoroznnyuk, V.V., Balatska, N. І. (2012) Deficyt vitamin D u naselennia Ukrainy ta factory ryzyku jogo rozvytku [Vitamin D deficiency in Ukrainian population and risk factors for its development]. Pain. Joints. Spine, 4 (08),

Lopes, V.M., Lopes, J.R., Brasileiro, J.P., Oliveira, I., Lacerda, R.P., Andrade, M.R., ….. Motta, L.A. (2016) Highly prevalence of vitamin D deficiency among Brazilian women of reproductive age. Arch Endocrinol Metab., 10. DOI: 10.1590/2359-3997000000216

Larijani, B., Hossein-Nezhad, A., Feizabad, E., Maghbooli, Z., Adibi, H., Ramezani, M., Taheri, E. (2016) Vitamin D deficiency, bone turnover markers and causative factors among adolescents: a cross-sectional study. J Diabetes Metab Disord. 12, 15-46.

Mazur, I. P. (2006) Kliniko-patohenetychni osoblyvosti perebihu zahvoruvan parodonta pry porushenni systemnogo kistkovogo metabolism ta ih korekcia [Clinicopathogenetic peculiarities of periodontal diseases progress during systemic bony metabolism violation and its correction]. D. Dissertation, Shupyk National Medical Academy of Postgraduate Education, Kyiv.

Zhurochko, E. І. (2011) Eksperementalne doslidgennia dystrofichno-dystruktyvnyh procesiv v tkanynah parodontu bilyh shchuriv reproductyvnoho viku za danymy osteometrii [Experimental research into the dystrophic and destructible processes in the peridental tissues of white rats of reproductive age based on osteometry data] Visnyk stomatologiy., 1, 2–9.

Dietrich, T., Joshipura, K.J., Dawson-Hughes, B. (2004) Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US population. Bischoff-Ferrari Am J Clin Nutr., 80(1), 108-113.

Amano Y, Komiyama K, Makishima M. (2009) Vitamin D and periodontal disease. J Oral Sci. 51(1), 11-20.

Boggess, K.A., Espinola, J.A., Moss, K., Beck, J., Offenbacher, S., Camargo, C.A. Jr. (2011) Vitamin D status and periodontal disease among pregnant women. J Periodontol., 82(2), 195-200

Garcia, M.N., Hildebolt, C.F., Miley, D.D., Dixon, D.A., Couture, R.A., Spearie, C.L., …. Civitelli, R. (2011) One-year effects of vitamin D and calcium supplementation on chronic periodontitis. J Periodontol., 82(1), 25-32.

Danylevskyi, N. F., Borysenko, А. V. (2011) Zabolevania parodonta [Periodontal disease]. К.: Zdorovia

Mazur, I. P., Makarenko, V. N. (2007) Vozrast-obuslovlennye rentgenomorfometricheskie izmenenia nizhnej chelusti u zhenshchin s generalisovannym parodontitom (kliniko-rentgenologicheskoe isledovanie) [Age-caused mandibular morphometric changes in women with generalized periodontitis (сlinical and radiological studies)]. Sovremennaia Stomatoloia [Modern dentistry], 4, 56–60.

Holick, M.F., Binkley, N.C., Bischoff-Ferrari, H.A., Gordon, CM., Hanley, D.A., Heaney, R.P., … Weaver, C.M. (2011) Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline. J. Clin. Endocrinol. Metab., 96 (7), 1911-1930.

Mazur, I.P., Povoroznnyuk, V.V., Novoshytskyy, V.E. (2016) Osoblyvosti kliniko-rentgenolohichnogo perebigy generalisovanogo parodontytu u pacientiv molodoho viku v zaleshnosti vid rivniz vitamin D [Features of clinical and radiological course of chronic periodontitis in young adult patients depending on the level of vitamin D]. Problems of osteology, 2, 25-29.

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