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Abstract
QUALITY OF LIFE IN PATIENTS WITH CHRONIC VENOUS DISEASES AND METHODS OF ITS IMPROVEMENT (review)
N.I. Pytetska
Assessment of the quality of life is one of the leading directions in modern medicine and continues to develop intensively, remaining an integral part of comprehensive analysis of new methods of diagnosis, treatment and prevention. This article provides information about the history of the concept "quality of life" and the ambiguity of terminology. Particular attention is paid to the necessity of studying this indicator in patients with chronic veins diseases, the relevance of this direction in the early stages of the disease, as well as medicines able to solve the main tasks of drug therapy, to restore work capacity and, as a result improve the patient's life quality.
Key words: quality of life, chronic venous diseases, diosmin.
ЯКІСТЬ ЖИТТЯ ХВОРИХ НА ХРОНІЧНІ ЗАХВОРЮВАННЯ ВЕН ТА МЕТОДИ ЇЇ ПОКРАЩЕННЯ (огляд)
Питецька Н.І.
Вивчення якості життя є одним із провідних напрямків сучасної медицини й продовжує інтенсивно розвиватись, залишаючись невід'ємною частиною всебічного аналізу нових методів діагностики, лікування і профілактики. У даній статті представлено інформацію про історію виникнення поняття «якість життя», неоднозначність термінології. Особливуувагу приділено необхідності оцінки даного показника у хворих на хронічні захворювання вен, актуальності цього напрямку на ранніх стадіях захворювання, а також лікарським засобам, які здатні вирішувати основні завдання медикаментозної терапії, відновлювати працездатність і підвищувати якість життя пацієнта.
Ключові слова: якість життя, хронічні захворювання вен, діосмін.
КАЧЕСТВО ЖИЗНИ БОЛЬНЫХ С ХРОНИЧЕСКИМИ ЗАБОЛЕВАНИЯМИ ВЕН И МЕТОДЫ ЕГО УЛУЧШЕНИЯ (обзор)
Питецкая Н.И.
Изучение качества жизни является одним из ведущих направлений современной медицины и продолжает интенсивно развиваться, оставаясь неотъемлемой частью всестороннего анализа новых методов диагностики, лечения и профилактики. В данной статье представлена информация об истории возникновения понятия «качество жизни», неоднозначности терминологии. Особое внимание уделено необходимости оценки данного показателя у больных хроническими заболеванияи вен, актуальности этого направления на ранних стадиях заболевания, а также лекарственным препаратам, которые способны решать основные задачи медикаментозной терапии, восстанавливать трудоспособность и повышать качество жизни пациента.
Ключевые слова: качество жизни, хронические заболевания вен, диосмин.
References
References
Karnofsky, D.A., Burchenal, J.H. (1949) The clinical evaluation of chemotherapeutic agents in Cancer. In Evaluation of chemotherapeutic agents, C.M. MacLeod (ed). New York: Columbia University Press, 191–205.
Elkington, J.R. (1966) Medicine and the quality of life. Annals of Internal Medicine, 64 (3), 711–714.
Novik, A.A., Ionova, T.I. (2007) Rukovodstvo po issledovaniyu kachestva zhizni v meditsinye [Guide to the study of quality of life in medicine]. 2-yе izdaniye / Pod red. akademika RAMN Yu.L. Shevchenko, M.: ZАО «ОLМА Меdia Grup», 320 p.
Melikyan, E.G., Milchakova, L.E., Geht, A.B. Kontseptsiya kachestva zhizni v epileptologii [The concept of quality of life in epileptology]. Zhurnal Nevrologii i Psihiatrii imeni C.C. Korsakova. Epilepsiya, vypusk 3, pp, 28–35.
Vnukov P.V. (2014) K voprosu ob otsenke reproduktivnoy sfery I rfchestva zhizni u muzhchin v posleoperatsionnom periode posle pahovoy gernioplastiki [On the issue of assessing the reproductive health and quality of life in men in the postoperative period after inguinal hernioplasty]. Nauka u molodyh– Eruditio Juvenium, no3, pp. 64-71.
Kubazhi, H., Magraui, U., Rakita, D.R. Solovyeva, A.V. (2012) Kachestvo zhizni bolnyh hronicheskoy obstruktivnoy boleznyu legkih v sochetanii s ishemicheskoy boleznyu serdtsa [Quality of life of patients with chronic obstructive pulmonary disease in combination with ischemic heart disease]. Rossiyskiy mediko-biologicheskiy vestnik imeni akademika I.P. Pavlova, no 3, pp. 87–93.
Anthony, S.J., Selkirk, E., Sung, L., Klasen, R.J., Dix, D., Scheinemann, K., Klassen, A.F. (2014) Considering quality of life for children with cancer: a systematic review of patient-reported outcome measures and the development of a conceptual model. Quality of Life Research, 3, 771–789.
Senkevich, N.Yu., Belyavskiy, A.S. (2000) Kachestvo zhizni predmet issledovaniya v pulmonologii [Quality of life is the subject of scientific research in pulmonology]. Terapevticheskiy arhiv, no 3, pp. 35−37.
The WHOQOL Group. World Health Organization Quality of Life Assessment (1996) What quality of life? World Health Forum, 17(4), 354–356.
Tsukanov, Yu.T, Tsukanov, A.Yu. (2003) Kachestvo zhizni bolnyh pri hirurgicheskom lechenii varikoznogo rasshireniya ven nizhnih konechnostey [Quality of life of patients with surgical treatment of varicose veins of lower extremities]. Hirurgiya, no 11, pp. 11–16.
Ivanov, E.V. (2015) Zavisimost kachestva zhizni patsientov s HBN klassa С4ОТ komplaentnosti pri ambulatornom lechenii [Dependence of quality of life of patients with CVI of C4OT class of compliance with outpatient treatment]. Materialy XXX Mezhdunarodnoy konferentsii Possiyskogo obshchestva angiologov I sosudistyh hirurgov, Sochi, 25-27615, pp. 212–214.
Zolotuhin, I.A.,Yumin, S.M., Leontev, S.G., Andriyashkin A.V., Kirienko A.I. (2011) Otdalennye rezultaty lecheniya patsientov, perenesshih tromboz glubokih ven nizhnih konechnostey [Long-term results of treatment of patients who underwent thrombosis of deep veins of lower extremities]. Flebologiya, tom 5, no1, pp. 27–33.
Beebe-Dimmer, J.L., Pfeife,r J.R., Engle, J.S., Schottenfeld D. (20050 The epidemiology of chronic venous insufficiency and varicose veins. // Annals of Epidemiology, 15(3), 175–184.
Murashko A.V. (2005) Zabolevanie ven i beremennost [Vein disease and pregnancy]. Ginekologiya, tom 7, no 5-6, pp. 316–318.
Serov V.N. Zharov E.V. (2014) Hronocheskaya venoznaya nedostatochnost [Chronic venous insufficiency]. Semeynaya meditsina, no 6, pp. 14–20.
Evans, C.J., Fowkes, F.G., Ruckley, C.V., Lee, A.J. (1999) Prevalence of varicose veins and chronic venous incificiency in men and women in the general population: Edinburg Vein Study // Journal of Epidemiology and Community Health, 53(3), 149–153.
Cesarone, M.R., Belcaro, G., Nicolaides, A.N., Geroulacos, G., Griffin, M., Incandela, N....Veller, M. (2002) 'Real' epidemiology of varicose veins and chronic venous diseases: the San Valentino Vascular Screening Project. Angiology, 53(2), 119–130.
Robertson, L., Evans, C., Fowkes, F.G. (2008) Epidemiology of chronic venous disease. Phlebology, 23(3), 103–111.
Kosinets, A.N., Petuhov, V.I. (2002) Varikoznoe rasshirenie ven nizhnih konechnostey [Varicose veins of lower extremities]. Vitebsk, VGMU, 200 p.
Birdwell, B. (1999) Recent clinical trials in the diagnosis ofdeep-veinthrombosis. // Current Opinion in Hematology, 6 (5), 275–279.
Klyscz, T., Junger, M., Schanz S., Janz, M., Rassner, G., Kohnen, R. (1998) Quality of life in chronic venous insufficiency (CVI). Results of a study with the newly developed Tubingen Questionnaire for measuring quality of life of patients with chronic venous insufficiency. Hautarzt, 49, 372 – 381.
Morgan, P.A., Franks, P.J., Moffatt, C.J. , Doherty, D.C., Connor, T.O., McCullagh, L., Hourican C. (2004) Illness behavior and social support in patients with chronic venous ulcers. Ostomy Wound Manage, 50 (1), 25–32.
Benigni, J.P., Sadoun, S., Allaert, F.A., Vin, F. (2003) Efficacy of Class 1 elastic compression stockings in the early stages of chronic venous disease. A comparative study. International Angiology, 22, 383–392.
Jantet, G. (2002) Chronic venous insufficiency: worldwide results of the RELIEF study. Reflux assessment and quality of life improvement with micronized Flavonoids. Angiology, 53, 245 –256.
Lozano, F.S., Launois, R. (2002) Quality of life (Spain and France): validation of the chronic venous insufficiency questionnaire (CIVIQ). Methods and Finding in Experimental and Clinical Pharmacology, 24, 425–429.
Eberhardt, R.T., Raffetto, J.D. (2005) Chronic venous insufficiency. Circulation, 111, 2398–2409.
Eklof, B., Rutherford, R.B., Bergan, J.J., Carpentier, P.H., Gloviczki, P., Kistner, R.L .... Wakefield T.W. (2004) Revision of the CEAP classification for chronic venous disorders: consensus statement. Journal of Vascular Surgery, 40, 1248–1252.
Casley-Smith, J.R., Casley-Smith, J. (1985) The effect of diosmin (a benzo-pyrone) upon some high-protein oedemas: lung contusion, burn and lymphoedema of the rat legs. Agents and Actions, 17, 14–20.
Tarahovskiy, Yu.S., Kim, Yu.A., Abdrasilov, B.S., Muzafarov, E.N. (2013) Flavonoidy: biohimiya, biophizika, meditsina: Pushchino, Sуnchrobook, 310 c.
Duperray, B., VierinJ., Pacheco, H. (1984) Pharmacokinetics and biochemical pharmacology of diosmin in animals. In Medical Therapy, J.A. Dormandy (ed.): Panminerva Medica, 182 – 185.
Araujo, D., Viana, F., Osswald, W. (1991) Diosmin Therapy Alters the in vitro metabolism of noradrenaline by the varicose human saphenous vein. Pharmacology Research, 24 (3), 253–256.
Zasorin, A.A., Makarova, N.P., Naritsina V.V. (2011) Vliyanie diosmina na microtsirkulyatsiyu pri vyalotekushchih ranah [Influence of diosmine on microcirculation with sluggish wounds]. Flebologiya, 1, 24–26.
Pokrovskiy, A.V., Sapelkin, C.V. (2005) Proizvodnye polusinteticheskogo diosmina v lechenii bolnyh s hronicheskoy nedostatochnostyu – rezultaty prospektivnogo issledovaniya s primeneniem preparata Flebodia 600 [Derivatives of semi-synthetic diosmine in treatment of patients with chronic venous insufficiency - results of a prospective study with using of Flebodia 600], Angiologiya i Sosudistaya hirurhiya, 11 (4), 73–84.
Batchvarov, I.V., Batselova, M.G. Damyanov I.I. (2010) One-year diosmin therapy (600 mg) in patients with chronic venous insufficiency – Results and analysis. Journal of Biomedical and Clinical Research, 3, 51–54.
Carpentier, P.H., Maricq, H.R., Biro, C., Poncot-Makinen, C.O., Franco, A. (2004) Prevalence, risk factors and clinical patterns of chronic venous disorders of lower limbs: A population-based study in France. Journal of Vascular Surgery., 40 (4), 650–659.
Macsimovic, Z.V., Macsimovic, M., Jadranin, D., Kuzmanovic, I., Andronovic O. (2008) Medicamentous treatment of chronic venous insufficiency using semisynthetic diosmin – a prospective study. Acta Chirurgica Iugoslavica, 55 (4), 53–59.
Shibelgut N.M., Baskakova T.B., Zaharov I.S., Mozes V.G. (2010) Effektivnost diosmina 600 mg pri provedenii profilactiki proingredientnogo techeniya varikoznoy bolezny malogo taza u beremennyh: rezultaty prostoho slepogo randomizirivannogo platsebo-kontrolirovannogo issledovaniya [Efficacy of the 600 mg diosamine in the prevention of the progressive course of varicose veins of the pelvic floor in pregnant women: the results of a simple, blind, randomized, placebo-controlled study]. Rossiyskiy vestnik akusherstva i ginekologii, 3, 27–32.
Lahno, I.V., Barannik, E.A., Tkachev A.E. (2011) Novaya metodologiya izucheniya effektov diosmina v perinatalnoy meditsine [A new methodology for studying the effects of diosmin in perinatal medicine]. Zdorove zhenshchiny, 10, 110–113.
Srinivasan, S., Pari, L. (2012) Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats. Chemico-Biologocal Interactions, 195 (1), 43–51.
Pari, L., Srinivasan, S. (2010) Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamideinduced diabetic rats. Biomedical Pharmacotherapy, 64, 477–481.
Silambarasan, T., Raja, B. (2012) Diosmin a bioflavonoid reverses alterations in blood pressure, nitric oxide, lipid peroxides and antioxidant status in DOCA-salt induced hypertensive rats. European Journal of Pharmacology, 679, 81–89.
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