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Abstract
PREDICTION OF UNFAVORABLE COURSE OF BRONCHOPULMONARY DYSPLASIA IN CHILDREN AT THE PRESENT STAGE 1Senatorova G.S., 1Chernenko L.M., 2Muratov G.R., 2Pushkar O.M. 1 Kharkiv national medical university, Kharkiv, Ukraine 2Public Health Care Institution «Kharkov Regional Clinical Children Hospital», Kharkiv, Ukraine Abstract. The article provides the results of vasoconstrictive and adaptogenic proteinases level analysis in children with bronchopulmonary dysplasia. It was shown that proteinase-proteinase inhibitor system plays a significant role in the development of cardiovascular complications in bronchopulmonary dysplasia and it can be regarded as markers of unfavorable course of bronchopulmonary dysplasia. Keywords: bronchopulmonary dysplasia, unfavorable course, components of proteinase-proteinase inhibitor system. ПРОГНОЗУВАННЯ НЕЗАДОВІЛЬНОГО ПЕРЕБІГУ БРОНХОЛЕГЕНЕВОЇ ДИСПЛАЗІЇ У ДІТЕЙ НА СУЧАСНОМУ ЕТАПІ 1Сенаторова А.С., 1Черненко Л.М., 2Муратов Г.Р., 2Пушкар О.М. 1Харківський національний медичний університет, м. Харків, Україна 2Комунальний заклад охорони здоровья «Харківська обласна клінічна дитяча лікарня», Харків, Україна Резюме. У статті наведено результати аналізу рівнів протеїназ вазоконстрикторної і апоптогенної дії у дітей з різними формами бронхолегеневої дисплазії. З’ясовано, що система протеиназа-інгібітор протеїназ грає істотну роль у розвитку кардіоваскулярних ускладнень, що можна розглядати в якості маркерів несприятливого перебігу бронхолегеневої дисплазії. Ключові слова: бронхолегенева дисплазія, протеїнази вазоконстрикторної дії, кардіоваскулярні ускладнення. ПРОГНОЗИРОВАНИЕ НЕУДОВЛЕТВОРИТЕЛЬНОГО ТЕЧЕНИЯ БРОНХОЛЕГОЧНОЙ ДИСПЛАЗИИ У ДЕТЕЙ НА СОВРЕМЕННОМ ЭТАПЕ 1Сенаторова А.С., 1Черненко Л.Н., 2Муратов Г.Р., 2Пушкарь Е.М. 1Харьковский национальный медицинский университет, г. Харьков, Украина 2Комунальний заклад охорони здоровья «Харківська обласна клінічна дитяча лікарня», Харків, Україна Резюме. В статье приведены результаты анализа уровней протеиназ вазоконстрикторного и аппоптогенного действия у детей с разными формами бронхолегочной дисплазии. Показано, что система протеиназа-ингибитор протеиназ играет значительную роль в развитии кардиоваскулярных осложнений, что можно рассматривать в качестве маркеров неблагоприятного течения бронхолегочной дисплазии. Ключевые слова: бронхолегочная дисплазия, неблагоприятное течение, компоненты системы протеиназ-ингибитор протеиназ.
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