SYNDROMAL CHARACTERISTICS OF DEPRESSIVE MANIFESTATIONS AMONG PATIENTS COGNITIVE IMPAIRMENTS IN DEPRESSIVE DISORDERS
PDF

Keywords

patients with cognitive impairment, depressive disorders, clinical and psychopathological features, recurrent depressive disorder, bipolar depressive disorder, prolonged depressive reaction.

Abstract

362 patients with cognitive impairment at depressive disorders were examined, of them 123 patients with recurrent depressive disorder (RDD), 141 patients with bipolar affective disorder (BAD) and 98 patients with prolonged depressive reaction (PDR). Differentiated clinical and psychopathological features of patients with cognitive impairment at depressive disorders were established: 1) combination of apathetic-adynamic, astheno-energetic and anxious symptom complexes;  predominance of moderate and major depressive episodes;  severity of apathy, subjective and objective signs of depression,  decrease in concentration and ability to feel were determined in patients with RDD; 2) combination of astheno-energetic, apathetic-adynamic, and melancholic symptom complexes;  predominance of moderate and major depressive episodes; the severity of apathy, subjective signs of depression, suicidal thoughts, insomnia and  decrease in concentration  in patients with BAD; 3) combination of anxious and apathetic-adynamic symptom complexes; the predominance of moderate and minor depressive episodes; the severity of internal stress, apathy, suicidal thoughts and loss of appetite  in patients with PDR.

https://doi.org/10.35339/ic.7.3.152-156
PDF

References

Comprehensive mental health action plan 2013-2020 (2013). [Electronic resource]. Geneva: WHO, 2013. Retrieved from: http://apps.who.int/gb/ebwha/pdf_files/WHA66/A66_R8-ru.pdf?ua=1 (Russian)

Eschweiler, G. W. (2017). Diagnostik und multimodale Therapie der Altersdepression: Diagnostics and multimodal treatment of depression in old age. Zeitschrift fur Gerontologie und Geriatrie, 50(2); 99– 105. DOI: 10.1007/s00391-016-1174-2.

Maslow, G. R., Dunlap K., Chung R. J. (2015) Depression and Suicide in Children and Adolescents. Pediatr Rev 36(7), 299–308; quiz 9-10. Epub 2015/07/03. DOI: 10.1542/pir.36-7-299.

McIntyre , R. S., Lophaven , S., Olsen , C. K. (2014). A randomized, double-blind, placebocontrolled study of vortioxetine on cognitive function in depressed adults. Int J Neuropsychopharmacol, 17(10), 1557–1567.

Maruta, N. O., Panko, T. V. Kalenska, G. Yu. (2017). Diagnostic criteria for depressive disorders at stages of providing medical aid. Ukrainian Newsletter of Psychoneurology, 25, 1(90), 135. (Ukr.)

Cotrena, C., Branco, L. D., Shansis, F. M. & Fonseca, R. P. (2016) Executive function impairmentsin depression and bipolar disorder: association with functional impairment and quality of life. J. Affect. Disord, 190, 744–753.

Olvet, D. M., Klein, D. N. & Hajcak, G. (2010). Depression symptom severity and errorrelated brain activity. Psychiatry Res. 179, 30–37.

Snyder, H. R. (2013). Major depressive disorder is associated with broad impairments on neuropsychological measures of executive function: a meta-analysis and review. Psychological Bull, 139, 81–132.

Practice Guideline for the treatment of patients with major depressive disorder. 3rd ed. Arlington,VA: American Psychiatric Association, 2010.

McIntyre, R. S., Cha, D. S., Soczynska, J. K. et al. (2013) Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions. Depress. Anxiety, 30(6) 515–527.,

Zuckerman, H., et al. (2018). Recognition and treatment of cognitive dysfunction in major depressive disorder. Front. Psychiatry, 9, 655.

McKnight, P. E., Kashdan, T. B. (2009). The importance of functional impairment to mental health outcomes: a case for reassessing our goals in depression treatment research. Clin. Psychol. Rev., 29(3), 243–259.

Montgomery, S. A., Asberg, M. (1979). A new depression scale designed to be sensitive to change. Br J. Psychiatry, 13(4), 382-389.

Copyright for articles published in the journal is regulated by the License Agreement for the use of a scientific article in the journal, which is concluded between the author of the article (Licensor) and Kharkov National Medical University (Licensee, publisher of the journal "Inter Collegas"). The licensor grants to the Licensee a non-exclusive non-exclusive license for the use of the article (a license that does not exclude the use of the article by the Licensor and the issuance of licenses to others for use of this article) on the terms and for the period specified in the contract. The licensor (the author of the article) grants the Licensee the right to reproduce the article (publication in the journal "Inter Collegas", publication, duplication, duplication or other reproduction of the article without limiting the circulation of copies, each copy of the article must contain the name of the Licensor; Of general information, including the publication of the article in full or in part on the Internet on the journal page, the right to use the metadata of the article (titles, full names of authors, annotations, bibliography eskih materials) through the dissemination and communication to the public, processing and systematization, as well as inclusion in various databases and in-formational system).

The licensor grants the licensee the right to transfer, store and process his personal data (full name, scientific degree, academic title, place of work and position, contact information of the authors) with the purpose of including them in the database in accordance with the Law of Ukraine No. 2297 - VI "on protection of personal data" from 01.06.2010.

Personal data and metadata of the article are provided for their storage and processing in various databases and information systems, including them in analytical and statistical reporting, creating sound relationships between the objects of works of science, literature and art with personal data, etc. on unlimited territory. The licensee has the right to transfer the specified data for processing and storage to third parties provided that such a fact is notified with the provision of information about the third party (name and address) to the Licensor.