uterus, endometrium, HIV, glands


The purpose of our study was to evaluate the features of endometrial restructuring when infected with the human immunodeficiency virus.

Materials and methods: The study involved sectional material taken from 60 women of reproductive age from 20 to 40 years.  Group 1 (30 women) consisted of women who were diagnosed with HIV infection. The control group comprised women (30) without concomitant HIV infection.

Results. An average diameter of the endometrial glands (proliferative type) was 8% smaller in HIV infection than in the comparison group. The minimum diameter of the endometrial glands (proliferative type) decreased by 1.73%, the maximum was 5.24% less in the HIV-infected group than in the comparison group. The wall thickness was reduced by 0.5% in HIV infection. The relative volume of the epithelium decreased by 2.4% (proliferative type). There were also significant changes in the structure of the glands and endometrium in secretory phase, as in the proliferative type. Thus, the average diameter of the glands decreased by 5%, the minimum volume of the glands by 5.01%, the maximum by 11.2%, the wall thickness by 1.5%, the relative volume of the epithelium by 9.5%, less in the group HIV-infected than in the comparison group. The thickness of the epithelium increased by 4.5% in the HIV-infected group compared with the comparison group.

Conclusion. The study evaluated features of endometrial restructuring in the presence of concomitant HIV infection in women.



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