Abstract
Latoguz S.I.
Treatment features of ciliary arrhythmia in patients with ischemic heart disease in combination with diabetes innocens
Kharkiv National Medical University, Ukraine
Abstract. We studied the efficacy of amiodarone in the 34 coronary heart disease patients suffering from paroxysmal or sustained atrial fibrillation. The functionality of the patients corresponded to II-III functional class NYHA. 18 patients had compensated diabetes II-type, mild to moderate severity. 19 patients (55.9%) had previous myocardial infarction within the period of 6 months of me-up to 2 years. Among them, 11 patients (32.4%) suffered from diabetes. Surveyed patients had exertional angina II-III functional class. The age of patients ranged from 43 to 59 years. Amiodarone has a pronounced antiarrhythmic effect in most patients with atrial fibrillation sufferers as coronary heart disease and ischemic heart disease and diabetes II-type. Treatment with amiodarone has no negative effect on cardiohemodynamics patients examined. Additional useful property of the drug - antianginal effect. Prophylactic administration of amiodarone for the prevention of recurrence of atrial fibrillation is less effective in patients with concomitant diabetes mellitus II-type.
Key words: coronary heart disease, diabetes, atrial fibrillation, amiodarone, aprovel, losartan.
С.И. Латогуз
Особенности лечения мерцательной аритмии у больных ишемической болезнью сердца и сахарным диабетом
Харьковский национальный медицинский университет, Украина
Резюме. Нами изучена эффективность амиодарона у 34-х больных ишемической болезнью сердца, страдающих пароксизмальной или устойчивой формой мерцательной аритмии. Функциональные возможности больных соответствовали II-III функциональному классу по NYHA. 18 больных страдали компенсированным сахарным диабетом II-го типа, легкой и средней степени тяжести. 19 больных (55,9%) ранее перенесли инфаркт миокарда в сроки от 6 месяцев до 2-х лет. Среди них 11 пациентов (32,4%) страдали сахарным диабетом. Обследованные пациенты страдали стенокардией напряжения II-III функционального класса. Возраст больных составил от 43 до 59 лет. Амиодарон оказывает выраженный антиаритмический эффект у большинства больных мерцательной аритмией, страдающих как ишемической болезнью сердца, так и ишемической болезнью сердца и сахарным диабетом II-го типа. Лечение амиодароном не оказывает отрицательного влияния на кардиогемодинамику у обследованных больных. Дополнительное полезное свойство препарата – антиангинальный эффект. Профилактический прием амиодарона с целью предупреждения рецидивов фибрилляции предсердий оказывается менее эффективным у больных с сопутствующим сахарным диабетом II-го типа.
Ключевые слова: ишемическая болезнь сердца, сахарный диабет, мерцательная аритмия, амиодарон, апровель, лозартан.
С.І. Латогуз
Особливості лікування миготливої аритмії у хворих ішемічною хворобою серця та цукровим діабетом
Харківський національний медичний університет, Україна
Резюме. Нами вивчена ефективність аміодарону у 34-х хворих на ішемічну хворобу серця, які страждають пароксизмальної або стійкою формою миготливої аритмії. Функціональні можливості хворих відповідали II-III функціонального класу за NYHA. 18 хворих страждали компенсованим цукровим діабетом II-го типу, легкого та середнього ступеня тяжкості. 19 хворих (55,9%) раніше перенесли інфаркт міокарда в терміни від 6 місяців до 2-х років. Серед них 11 пацієнтів (32,4%) страждали на цукровий діабет. Обстежені пацієнти страждали стенокардією напруги II-III функціонального класу. Вік хворих склав від 43 до 59 років. Аміодарон має виражений антиаритмічний ефект у більшості хворих миготливою аритмією, які страждають як ішемічною хворобою серця, так і ішемічною хворобою серця і цукровим діабетом II-го типу. Лікування аміодароном не робить негативного впливу на кардіогемодинаміку у обстежених хворих. Додаткове корисна властивість препарату - антиангінальний ефект. Профілактичний прийом аміодарону з метою попередження рецидивів фібриляції передсердь виявляється менш ефективним у хворих з супутнім цукровим діабетом II-го типу.
Ключові слова: ішемічна хвороба серця, цукровий діабет, миготлива аритмія, аміодарон, апровель, лозартан.
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