Comparative analysis of the role of domestic allergens in atopic dermatitis etiology in children

Abstract

Shmulich V.K., Uryvayva M.K., Lupaltsova O.S., Staruseva V.V., Rybka O.S., Shmulich O.V., Kryvenko L.S.
Comparative analysis of the role of domestic allergens in atopic dermatitis etiology in children
Kharkiv National Medical University, Ukraine

Abstract. Four hundred and thirty-eight children aged 4 to 18 suffering from atopic dermatitis in the sustained remission phase in the course of the disease were studied using the skin prick testing technique. Prevalence of children of pre-school and primary school age with the atopic dermatitis was established. Skin acariasis caused by Dermatophagoides farinae mites prevails which can be used to optimize specific immunotherapy of atopic of dermatitis in children. Children of the senior school age were the least sensitive to A. Daphnia magna. Suitability of the start elimination therapy was proved. The detected age and sex etiological features of (atopic dermatitis) AD in the large population of children related mostly to the prevailing role of domestic triggers suggest the urgent necessity to eliminate the allergens in the residential premises where children suffering from allergic diseases live, as well as in the places where healthy children live, since the long contact with the indoor allergens is potentially hazardous regarding sensitization formation.
Key words: atopic dermatitis, domestic allergens, children.


Шмуліч В.К., Уриваєва М.К., Лупальцова О.С., Старусева В.В., Рибка О.С., Шмуліч О.В., Кривенко Л.С.
Порівняльна характеристика значущості побутових алергенів в етіології атопічного дерматиту у дітей.
Харківський національний медичний університет, Україна

Резюме. Методом prick-test обстежено 438 дітей віком від 4 до 18 років, хворих на атопічний дерматит у період стійкої ремісії встановлено перевагу у захворюваності атопічним дерматитом серед дітей дошкільного та раннього шкільного віку. Серед шкірних акаріазів превалюютьвикликані кліщами роду Dermatophagoides farina, що може бути використано з метою оптимізації специфічної імунотерапії атопічного дерматиту у дітей. Діти старшого шкільного віку найменш чутливі до A.Daphnia magna. Доказана доцільність стартової елімінаційної терапії.
Ключові слова: атопічний дерматит, побутові алергени, діти.


Шмулич В.К., Урываева М.К., Лупальцова О.С., Старусева В.В., Рыбка Е.С., Шмулич О.В., Кривенко Л.С.
Сравнительная характеристика значимости бытовых аллергенов в этиологии атопического дерматита у детей.
Харьковский национальный медицинский университет, Украина

Резюме. Методом prick-test обследовано 438 детей в возрасте от 4 до 18 лет, больных атопическим дерматитом в фазе стойкой ремиссии в течении заболевания. Установлено преобладание в заболеваемости атопическим дерматитом детей дошкольного и раннего школьного возраста. Среди кожных акориазов преобладают вызванные клещами рода Dermatophagoides farina, что может быть использовано с целью оптимизации специфической иммунотерапии атопического дерматита у детей. Дети старшего школьного возраста наименее чувствительны к A.Daphnia magna. Доказана необходимость в стартовой элиминационной терапии.
Ключевые слова: атопический дерматит, бытовые аллергены, дети.

https://doi.org/10.35339/ic.2.2.205-211
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