SIRENOMELIA AS EXAMPLE OF LIMB MALFORMATION

Abstract

SIRENOMELIA AS EXAMPLE OF LIMB MALFORMATION

Nikolaenko E.U., Gargin V.V.

Kharkov National Medical University, Ukraine

Abstract.
The article is devoted for syndrome mermaid - very severe syndrome of caudal regression (complex malformation the caudal portion of the embryo), which
is a rare severe congenital malformation of the distal spine and spinal cord (his clinical picture is accompanied by hypoplasia of the lower half of the trunk
and extremities, a fusion of the lower limbs). We discuss the etiology, classification, pathological anatomy, the prognosis of this disease.
Key words:
fetus, sirenomelia, congenital defect

 

Сиреномелія як приклад пороку розвитку кінцівок

Николаенко Е.Ю., Гаргін В.В.

Харківський національний медичний університет, Україна

Резюме.
Стаття присвячена синдрому русалки - вкрай важкій формі синдрому каудальної регресії (комплекс вад розвитку каудальної частини ембріона),
який, у свою чергу, є рідкісним важким уродженим пороком розвитку дистального відділу хребта та спинного мозку (його клінічна картина
захворювання супроводжується гіпоплазією нижньої половини тулуба і кінцівок, злиття нижніх кінцівок). Обговорюються етіологія, класифікація,
патологічна анатомії, прогноз даної патології.
Ключові слова:
плід, сиреномелія, вада розвитку

 

Сиреномелия как пример порока развития конечностей

Николаенко Е.Ю., Гаргин В.В.

Харьковский национальный медицинский университет, Украина

Резюме.
Статья посвящена синдрому русалки – крайне тяжелой форме синдрома каудальной регрессии (комплекс пороков развития каудальной части
эмбриона), который, в свою очередь, является редким тяжелым врожденным пороком развития дистального отдела позвоночника и спинного
мозга (его клиническая картина заболевания сопровождается гипоплазией нижней половины туловища и конечностей, слияние нижних
конечностей). Обсуждаются этиология, классификация, патологическая анатомии, прогноз данной патологии.
Ключевые слова:
плод, сиреномелия, врожденный дефект

https://doi.org/10.35339/ic.2.3.317-322
PDF

References

Cuillier F., Mardamootoo D., Lamarque M., Cerisier S., Bideaut J. Three-dimensional sonography of sirenomelia at 10 and 12 weeks' gestation // J

Ultrasound Med. – 2013 - 32(9). – P.1678-1680.

Fadhlaoui A., Khrouf M., Gaigi S., Zhioua F., Chaker A. The sirenomelia sequence: a case history // Clin Med Insights Case Rep. – 2010. – 3.

P.41-49.

Horikoshi T., Kikuchi A., Tatematsu M., Matsumoto Y., Hayashi A., Unno N. Two cases of a fetus with sirenomelia sequence // Congenit Anom

(Kyoto). – 2005. - 45(3). – P.93-95.

Nisenblat V., Leibovitz Z., Paz B., Shapiro I., Degani S., Ohel G. Dizygotic twin pregnancy discordant for sirenomelia // J Ultrasound Med. – 2007.

- 26(1). – P.97-103.

Ono T., Katsura D., Tsuji S., Yomo H., Ishiko A., Inoue T., Kita N., Takahashi K., Murakami T. Prenatal diagnosis of sirenomelia in the late second

trimester with three-dimensional helical computed tomography // Tohoku J Exp Med. – 2011. - 225(2). – P.85-87.

Sepulveda W., Martinez J.L., Moenne K. Sirenomelia (symelia dipus) // Pediatr Radiol. – 2005. - 35(9). P.931-933.

Su D., Yao Q Sirenomelia with upper limb malformation: a case report and review of the literature // Clin Exp Obstet Gynecol. – 2015. - 42(4).

P.537-539.

Tayel S.M., Fawzia M.M., Al-Naqeeb N.A., Gouda S., Al Awadi S.A., Naguib K.K. A morpho-etiological description of congenital limb anomalies //

Ann Saudi Med. – 2005. - 25(3). – P.219-227.

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