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Abstract
GENDER CHARACTERISTICS OF DEPRESSIVE SYMPTOMS OF DEMENTIA IN PATIENTS WITH SUICIDAL BEHAVIOR
Mudrenko I.H.
Dementia is in most cases comorbid, which greatly reduces the quality of patients’ life and increases the risk of suicidal manifestations.
The aim of the study is to determine gender characteristics of depressive symptoms in patients with various clinical types of dementia with high suicide risk.
The object and methods of research. Thestudy involved examination of 105 patients with dementia of different types (due to Alzheimer's disease, vascularandmixedone) with high suicide risk using the HamiltonDeppression Rating Scale (HDRS).
Results of theresearch. Statistical analysisshowedthat a high degree of depression is a markerof suicidal risk in men with a vascular type of dementia, and in women with a mixed type of dementia. Verbalization (statement of suicidal intentions, thoughts) and the behavioral component of suicidal behavior (attempts) with a pronounced torpidity of mental processes are typical for men with Alzheimer's disease and vascular dementia and for women with a mixed type of dementia.
In women, affective oscillations during the day increased SR in Alzheimer's disease, and frequent wakening at night in mixed dementia. Physical limitations and inability to perform work, the problems with sexual vigor can be considered a psychogenic factor of high SR in men with vascular impairment.
Key words:dementia in Alzheimer’s disease, vascular dementia, mixed dementia, gender differences, depressive symptoms, predictors of suicidal behavior.
Резюме
ГЕНДЕРНІ ОСОБЛИВОСТІ ДЕПРЕСИВНОЇ СИМПТОМАТИКИ В СТРУКТУРІ ДЕМЕНЦІЙ У ОСІБ З СУЇЦИДАЛЬНОЮ ПОВЕДІНКОЮ
Мудренко І.Г.
Деменція у більшості випадків коморбідна з депресією, що значно знижує якість життя хворих та підвищує ризик суїцидальних проявів у даної категорії хворих.
Метою нашого дослідження є визначення гендерних особливостей депресивної симптоматики у хворих з різними клінічними варіантами деменції з високим ризиком суїциду. Об’єкт та методи дослідження. Всього обстежено 105 пацієнтів з деменціями різних типів (внаслідок хвороби Альцгеймера, судинною, змішаною) з високим суїцидальним ризиком за допомогою шкали Гамільтона для оцінки депресії (HDRS).
На підставі статистичного аналізу встановлено, що високий ступінь депресії є маркером суїцидального ризику у чоловіків з судинним типом деменціїі, а у жінок зі змішаним типом дементного процесу. Вербалізація (висловлювання суїцидальних намірів, думок) та поведінковий компонент суїцидальної поведінки (спроби) на фоні вираженої торпідності психічних процесів притаманні для чоловіків з хворобою Альцгеймера та судинною деменцією та для жінок зі змішаним типом дементного враження. У жінок підвищували СР при хворобі Альцгеймера афективні коливання на протязі доби, а при змішаній деменції - часті пробудження вночі. Можна припустити, що психогенним чинником високого СР у чоловіків з судинним враженням є фізичні обмеження та нездатність до виконання робіт, проблеми з потенцією.
Ключові слова:деменція при хворобі Альцгеймера, судинна, змішана, гендерні відмінності, депресивна симптоматика, пре диктори суїцидальної поведінки.
Резюме
ГЕНДЕРНЫЕ ОСОБЕННОСТИ ДЕПРЕССИВНОЙ СИМПТОМАТИКИ В СТРУКТУРЕ ДЕМЕНЦИИ У ЛИЦ С СУИЦИДАЛЬНЫМ ПОВЕДЕНИЕМ
Мудренко И.Г.
Введение. Деменция в большинстве случаев коморбидна с депрессией, что значительно снижает качество жизни больных и повышает риск суицидальных проявлений у данной категории больных.
Целью нашего исследования явилось определение гендерных особенностей депрессивной симптоматики у больных с различными клиническими вариантами деменции с высоким риском суицида. Обследовано 105 пациентов с деменцией различных типов (вследствие болезни Альцгеймера, сосудистой, смешанной) с высоким суицидальным риском (СР) с помощью шкалы Гамильтона для оценки депрессии (HDRS).
На основании статистического анализа установлено, что высокая степень депрессии является маркером суицидального риска у мужчин с сосудистым типом деменциии, а у женщин со смешанным типом дементного процесса. Вербализация (высказывания суицидальных намерений, мыслей) и поведенческий компонент суицидального поведения (попытки) на фоне выраженной торпидности психических процессов присущи для мужчин с болезнью Альцгеймера и сосудистой деменцией и для женщин со смешанным типом деменции. У женщин повышали СР при болезни Альцгеймера аффективные колебания в течение суток, а при смешанной деменции - частые пробуждения ночью. Можно предположить, что психогенным фактором высокого СР у мужчин с сосудистым поражением головного мозга являются физические ограничения и неспособность к выполнению работ, проблемы с потенцией.
Ключевые слова: деменция при болезни Альцгеймера, сосудистая, смешанная, гендерные различия, депрессивная симптоматика, предикторы суицидального поведения.
References
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