The article is devoted to the problem of coronavirus disease COVID-19 with emphasis on the nutritional status of patients. An analytical review of recent publications related to aspects of nutritional support for people in outpatient and inpatient treatment for COVID-19 is presented. The article highlights the pathogenetic justification of the relationship between the immune response and metabolic balance of the body, the optimal content of trace elements, vitamins, components of lipid metabolism. The importance of nutrition as a strategy to support human immune function is considered. Methods for determining the adequate energy balance of patients with severe COVID-19 are presented. Groups of foods and key nutrients that may affect the consequences and clinical course of respiratory infections are described.
The importance of assessing and optimizing nutritional status to improve the clinical course and consequences of COVID-19 in patients with comorbid pre-existing non-communicable diseases, such as diabetes, cardiovascular disease, obesity with systemic inflammation, is emphasized
Abdulzahra Hussain, Kamal Mahawar, Zefeng Xia, Wah Yang, Shamsi EL-Hasanie. (2020). Obesity and mortality of COVID-19. Meta-analysis. Obes Res Clin Pract., 14(4), 295-300. doi: 10.1016/j.orcp.2020.07.002.
Barry M Popkin, Shufa Du, William D Green, Melinda A Beck, Taghred Algaith, Christopher H Herbst,… Meera Shekar. (2020). Іndividuals with obesity and COVID-19: A global perspective on the epidemiology and biological relationships. Obes Rev., 21(11):e13128. doi: 10.1111/obr.13128.
D O'Shea, M Corrigan, M R Dunne, R Jackson, C Woods, G Gaoatswe,…A E Hogan. (2013). Changes in human dendritic cell number and function in severe obesity may contribute to increased susceptibility to viral infection. Int J Obes (Lond), 37(11), 1510-3. doi: 10.1038/ijo.2013.16. Epub 2013 Feb 26.
Rukhsana Gul, Uh-Hyun Kim, Assim A Alfadda. (2021). Renin-angiotensin system at the interface of COVID-19 infection. Eur J Pharmacol, 5, 890:173656. doi: 10.1016/j.ejphar.2020.173656. Epub 2020 Oct 18.
Hidekatsu Yanai. (2020). Metabolic Syndrome and COVID-19. Cardiol Res., 11(6), 360-365. doi: 10.14740/cr1181. Epub 2020 Nov 2.
Adrian F Gombart, Adeline Pierre, Silvia Maggini. (2020). A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients., 12(1), 236. doi: 10.3390/nu12010236.
Inga Wessels, Martina Maywald, Lothar Rink. (2017) Zinc as a gatekeeper of immune function. Nutrients., 9, 1286.doi:10.3390/nu9121286.
Maria Maares, Hajo Haase. (2016). Zinc and immunity: An essential interrelation. Arch. Biochem. Biophys., 611, 58–65. doi: 10.1016/j.abb.2016.03.022. Epub 2016 Mar 26.
Nour Zahi Gammoh, Lothar Rink. (2017) Zinc in infection and inflammation. Nutrients, 9, 624. doi: 10.3390/nu9060624.
Yuxin Chen, Zhongyang Zhou, Wang Min. (2018). Mitochondria, Oxidative Stress and Innate Immunity. Front Physiol., 9, 1487. doi:10.3389/fphys.2018.01487
Mini Chandra, Manikandan Panchatcharam, Sumitra Miriyala. (2015). Manganese superoxide dismutase: guardian of the heart dysfunction. MOJ Anatomy & Physiology., 1(2), 27‒28. DOI: 10.15406/mojap.2015.01.00006
Ibrahim Elmadfa, Alexa L Meyer. (2019) The Role of the Status of Selected Micronutrients in Shaping the Immune Function. Endocr Metab Immune Disord Drug Targets., 19(8), 1100-1115. doi: 10.2174/1871530319666190529101816
Zhiyi Huang, Yu Liu, Guangying Qi, David Brand, Song Guo Zheng. (2018) Role of vitamin A in the immune system. J Clin Med, 7(9) doi:10.3390/jcm7090258.PMC6162863
Ga Young Lee, Sung Nim Han. (2018). The role of vitamin E in immunity. Nutrients, 10, 614. doi:10.3390/nu10111614.
Alpha A Fowler 3rd, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday,…Matthew Halquist. (2019). Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial. JAMA., 322(13), 1261–1270. doi:10.1001/jama.2019.11825.
Kui Liu, Yuan-Yuan Fang, Yan Deng, Wei Liu, Mei-Fang Wang, Jing-Ping Ma,…Hui-Guo Liu. (2020). Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl)., 133(9), 1025-1031. doi: 10.1097/CM9.0000000000000744.
Anitra C Carr. (2020). A new clinical trial to test high-dose vitamin C in patients with COVID-19. Crit Care, 24(1), 133. doi: 10.1186/s13054-020-02851-4.
Mradul Mohan, Jerin Jose Cherian, Amit Sharma. (2020). Exploring links between vitamin D deficiency and COVID-19. PLoS Pathog., 16(9): e1008874. Published online 2020 Sep 18. doi: 10.1371/journal.ppat.1008874
John P Bilezikian, Daniel Bikle, Martin Hewison, Marise Lazaretti-Castro, Anna Maria Formenti, Aakriti Gupta,… Andrea Giustina. (2020). MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19. Eur J Endocrinol, 183(5), 133-147. doi: 10.1530/EJE-20-0665.
Marc Birringer, Stefan Lorkowski. (2019). Vitamin E: Regulatory role of metabolites. IUBMB Life., 71(4), 479-486. doi: 10.1002/iub.1988. Epub 2018 Dec 22.
Ye Gao, Huawei Zhang, Lingchun Luo, Jing Lin, Dan Li, Sisi Zheng,… Shengwei Jin. (2017). Resolvin D1 improves the resolution of inflammation via activating NF- κBp50/p50–mediated cyclooxygenase-2 expression in acute respiratory distress syndrome. J. Immunol., 199, 2043–2054. doi: 10.4049/jimmunol.1700315.
Ho Pan Sham, Katherine H. Walker, Raja-Elie E. Abdulnour, Nandini Krishnamoorthy, David N. Douda, Paul C. Norris,… Bruce D. Levy. (2018). 15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 induce NF- κB regulators in bacterial pneumonia. J. Immunol., 200, 2757–2766. doi: 10.4049/jimmunol.1602090
Ahilanandan Dushianthan, Rebecca Cusack, Victoria A Burgess, Michael Pw Grocott, Philip Calder. (2020). Immunonutrition for Adults With ARDS: Results From a Cochrane Systematic Review and Meta-Analysis. Respiratory Care January, 65 (1), 99-110; DOI: https://doi.org/10.4187/respcare.06965
Emanual Maverakis, Kyoungmi Kim, Michiko Shimoda, M. Eric Gershwinc, Forum Patel, Reason Wilken,… Carlito B. Lebrilla. (2015). Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review. Journal of Autoimmunity, 57, 1-13. https://doi.org/10.1016/j.jaut.2014.12.002
Copyright for articles published in the journal is regulated by the License Agreement for the use of a scientific article in the journal, which is concluded between the author of the article (Licensor) and Kharkov National Medical University (Licensee, publisher of the journal "Inter Collegas"). The licensor grants to the Licensee a non-exclusive non-exclusive license for the use of the article (a license that does not exclude the use of the article by the Licensor and the issuance of licenses to others for use of this article) on the terms and for the period specified in the contract. The licensor (the author of the article) grants the Licensee the right to reproduce the article (publication in the journal "Inter Collegas", publication, duplication, duplication or other reproduction of the article without limiting the circulation of copies, each copy of the article must contain the name of the Licensor; Of general information, including the publication of the article in full or in part on the Internet on the journal page, the right to use the metadata of the article (titles, full names of authors, annotations, bibliography eskih materials) through the dissemination and communication to the public, processing and systematization, as well as inclusion in various databases and in-formational system).
The licensor grants the licensee the right to transfer, store and process his personal data (full name, scientific degree, academic title, place of work and position, contact information of the authors) with the purpose of including them in the database in accordance with the Law of Ukraine No. 2297 - VI "on protection of personal data" from 01.06.2010.
Personal data and metadata of the article are provided for their storage and processing in various databases and information systems, including them in analytical and statistical reporting, creating sound relationships between the objects of works of science, literature and art with personal data, etc. on unlimited territory. The licensee has the right to transfer the specified data for processing and storage to third parties provided that such a fact is notified with the provision of information about the third party (name and address) to the Licensor.