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Abstract
The article is devoted to the problem of coronavirus disease COVID-19 with emphasis on the nutritional status of patients. An analytical review of recent publications related to aspects of nutritional support for people in outpatient and inpatient treatment for COVID-19 is presented. The article highlights the pathogenetic justification of the relationship between the immune response and metabolic balance of the body, the optimal content of trace elements, vitamins, components of lipid metabolism. The importance of nutrition as a strategy to support human immune function is considered. Methods for determining the adequate energy balance of patients with severe COVID-19 are presented. Groups of foods and key nutrients that may affect the consequences and clinical course of respiratory infections are described.
The importance of assessing and optimizing nutritional status to improve the clinical course and consequences of COVID-19 in patients with comorbid pre-existing non-communicable diseases, such as diabetes, cardiovascular disease, obesity with systemic inflammation, is emphasized
References
References:
Abdulzahra Hussain, Kamal Mahawar, Zefeng Xia, Wah Yang, Shamsi EL-Hasanie. (2020). Obesity and mortality of COVID-19. Meta-analysis. Obes Res Clin Pract., 14(4), 295-300. doi: 10.1016/j.orcp.2020.07.002.
Barry M Popkin, Shufa Du, William D Green, Melinda A Beck, Taghred Algaith, Christopher H Herbst,… Meera Shekar. (2020). Іndividuals with obesity and COVID-19: A global perspective on the epidemiology and biological relationships. Obes Rev., 21(11):e13128. doi: 10.1111/obr.13128.
D O'Shea, M Corrigan, M R Dunne, R Jackson, C Woods, G Gaoatswe,…A E Hogan. (2013). Changes in human dendritic cell number and function in severe obesity may contribute to increased susceptibility to viral infection. Int J Obes (Lond), 37(11), 1510-3. doi: 10.1038/ijo.2013.16. Epub 2013 Feb 26.
Rukhsana Gul, Uh-Hyun Kim, Assim A Alfadda. (2021). Renin-angiotensin system at the interface of COVID-19 infection. Eur J Pharmacol, 5, 890:173656. doi: 10.1016/j.ejphar.2020.173656. Epub 2020 Oct 18.
Hidekatsu Yanai. (2020). Metabolic Syndrome and COVID-19. Cardiol Res., 11(6), 360-365. doi: 10.14740/cr1181. Epub 2020 Nov 2.
Adrian F Gombart, Adeline Pierre, Silvia Maggini. (2020). A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients., 12(1), 236. doi: 10.3390/nu12010236.
Inga Wessels, Martina Maywald, Lothar Rink. (2017) Zinc as a gatekeeper of immune function. Nutrients., 9, 1286.doi:10.3390/nu9121286.
Maria Maares, Hajo Haase. (2016). Zinc and immunity: An essential interrelation. Arch. Biochem. Biophys., 611, 58–65. doi: 10.1016/j.abb.2016.03.022. Epub 2016 Mar 26.
Nour Zahi Gammoh, Lothar Rink. (2017) Zinc in infection and inflammation. Nutrients, 9, 624. doi: 10.3390/nu9060624.
Yuxin Chen, Zhongyang Zhou, Wang Min. (2018). Mitochondria, Oxidative Stress and Innate Immunity. Front Physiol., 9, 1487. doi:10.3389/fphys.2018.01487
Mini Chandra, Manikandan Panchatcharam, Sumitra Miriyala. (2015). Manganese superoxide dismutase: guardian of the heart dysfunction. MOJ Anatomy & Physiology., 1(2), 27‒28. DOI: 10.15406/mojap.2015.01.00006
Ibrahim Elmadfa, Alexa L Meyer. (2019) The Role of the Status of Selected Micronutrients in Shaping the Immune Function. Endocr Metab Immune Disord Drug Targets., 19(8), 1100-1115. doi: 10.2174/1871530319666190529101816
Zhiyi Huang, Yu Liu, Guangying Qi, David Brand, Song Guo Zheng. (2018) Role of vitamin A in the immune system. J Clin Med, 7(9) doi:10.3390/jcm7090258.PMC6162863
Ga Young Lee, Sung Nim Han. (2018). The role of vitamin E in immunity. Nutrients, 10, 614. doi:10.3390/nu10111614.
Alpha A Fowler 3rd, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday,…Matthew Halquist. (2019). Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial. JAMA., 322(13), 1261–1270. doi:10.1001/jama.2019.11825.
Kui Liu, Yuan-Yuan Fang, Yan Deng, Wei Liu, Mei-Fang Wang, Jing-Ping Ma,…Hui-Guo Liu. (2020). Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl)., 133(9), 1025-1031. doi: 10.1097/CM9.0000000000000744.
Anitra C Carr. (2020). A new clinical trial to test high-dose vitamin C in patients with COVID-19. Crit Care, 24(1), 133. doi: 10.1186/s13054-020-02851-4.
Mradul Mohan, Jerin Jose Cherian, Amit Sharma. (2020). Exploring links between vitamin D deficiency and COVID-19. PLoS Pathog., 16(9): e1008874. Published online 2020 Sep 18. doi: 10.1371/journal.ppat.1008874
John P Bilezikian, Daniel Bikle, Martin Hewison, Marise Lazaretti-Castro, Anna Maria Formenti, Aakriti Gupta,… Andrea Giustina. (2020). MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19. Eur J Endocrinol, 183(5), 133-147. doi: 10.1530/EJE-20-0665.
Marc Birringer, Stefan Lorkowski. (2019). Vitamin E: Regulatory role of metabolites. IUBMB Life., 71(4), 479-486. doi: 10.1002/iub.1988. Epub 2018 Dec 22.
Ye Gao, Huawei Zhang, Lingchun Luo, Jing Lin, Dan Li, Sisi Zheng,… Shengwei Jin. (2017). Resolvin D1 improves the resolution of inflammation via activating NF- κBp50/p50–mediated cyclooxygenase-2 expression in acute respiratory distress syndrome. J. Immunol., 199, 2043–2054. doi: 10.4049/jimmunol.1700315.
Ho Pan Sham, Katherine H. Walker, Raja-Elie E. Abdulnour, Nandini Krishnamoorthy, David N. Douda, Paul C. Norris,… Bruce D. Levy. (2018). 15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 induce NF- κB regulators in bacterial pneumonia. J. Immunol., 200, 2757–2766. doi: 10.4049/jimmunol.1602090
Ahilanandan Dushianthan, Rebecca Cusack, Victoria A Burgess, Michael Pw Grocott, Philip Calder. (2020). Immunonutrition for Adults With ARDS: Results From a Cochrane Systematic Review and Meta-Analysis. Respiratory Care January, 65 (1), 99-110; DOI: https://doi.org/10.4187/respcare.06965
Emanual Maverakis, Kyoungmi Kim, Michiko Shimoda, M. Eric Gershwinc, Forum Patel, Reason Wilken,… Carlito B. Lebrilla. (2015). Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review. Journal of Autoimmunity, 57, 1-13. https://doi.org/10.1016/j.jaut.2014.12.002
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