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Abstract
Lipko O.P., Shcherbina I.N., Dynnik O.O., Skorbach O.I., Borodai I.S.
Characteristic features in the system of hemostasis of patients with abnormal uterine bleeding at puberty
Kharkiv National Medical University, Ukraine
Abstract. The article is aimed at clarifying the features of the hemostasis system in patients with abnormal uterine bleeding (AUB) in adolescence. The features of the state of the blood coagulation system in patients with AUB which are not connected with blood diseases were identify. It was found that only in a small number of patients abnormalities in the hemostatic system do not detected. Most patients have defects in coagulation and anticoagulation systems.The greatest changes occur at the ΙΙ and ΙΙΙ phases of hemostasis. Some features, characteristic of patients from different clinical groups: dependence on the duration, the presence of concomitant somatic pathology, and the level of estrogen intenseness have been revealed in the study. With the rise in the bleeding duration the number of patients with hypercoagulation manifestations in the hemostatic system also increases. In adolescents with concomitant somatic pathology and hyperestrogenemia manifestations of increased blood coagulation have been registered more often already at the first phase of the coagulation process.
Key words: abnormal uterine bleeding, adolescent girls, the system of hemostasis.
Липко О.П., Щербина И.Н., Дынник А.А., Скорбач Е.И., Бородай И.С.
Особенности системы гемостаза у больных с аномальными маточными кровотечениями пубертатного пери ода
Харьковский национальный медицинский университет, Украина
Резюме. Статья посвячена изучению системы гемостаза у больных с аномальными маточными кровотечениями пубертатного периода. Выявлены особенности состояния свертывающей системы крови у пациенток с АМК, не связанные с заболеваниями крови. Выяснено что только у незначительного количества больных на фоне АМК не регистрируется отклонений в системе гемостаза, у большинства отмечаются дефекты в свертывающей и противосвертывающей системах. Наибольшие изменения происходят во ΙΙ и ΙΙΙ фазе гемостаза. Выявлены особенности характерные для больных разных клинических групп, зависимость от длительности кровотечения, наличия сопутствующей соматической патологии, уровня эстрогенной насыщенности. При увеличении длительности кровотечения возрастает количество больных с проявлениями гиперкоагуляции в системе гемостаза. У подростков с сопутствующей соматической патологией и гиперэстрогенией чаще отмечались проявления повышения свертываемости уже в первой фазе коагуляционного процесса.
Ключевые слова: аномальные маточные кровотечения, девочки-подростки, система гемостаза.
Ліпко О.П., Щербіна І.М., Диннік О.О., Скорбач О.І., Бородай І.С.
Особливості системи гемостазу у хворих з аномальними матковими кровотечами пубертатного періоду
Харківський національний медичний університет, Україна
Резюме. Стаття присвячена вивченню системи гемостазу у хворих з аномальними матковими кровотечами пубертатного періоду. Виявлено особливості стану системи згортання крові у пацієнток з АМК, які не пов'язані із захворюваннями крові. З'ясовано, що тільки у незначної кількості хворих на тлі АМК не реєструється відхилень у системі гемостазу, у більшості відзначаються дефекти в системі згортання та протизгортання крові. Найбільші зміни відбуваються у ΙΙ і ΙΙΙ фазі гемостазу. Виявлено особливості характерні для хворих різних клінічних груп, залежність від тривалості кровотечі, наявності супутньої соматичної патології, рівня естрогенної насиченості. При збільшенні тривалості кровотечі зростає кількість хворих з проявами гіперкоагуляції в системі гемостазу. У підлітків із супутньою соматичною патологією та гіперестрогенією частіше відзначалися прояви підвищення згортання вже в першій фазі коагуляционного процесу.
Ключові слова: аномальні маткові кровотечі, дівчатка-підлітки, система гемостазу.
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